Scientists at the University of Bristol have shown that a strain of bacteria called Clostridium difficile can kill brain cells and destroy the brain’s ability to function in the body.
The bacteria was found to be able to trigger a brain attack in mice that had been treated with a vaccine for the bacterium.
The research, published today in Science Translational Medicine, could lead to a vaccine against this devastating illness.
The researchers have developed a vaccine to protect people against Clostidium diffis, which is thought to be caused by the same strain of the bacteria that causes the common cold and can cause brain inflammation.
They found that the vaccine could kill mice for months or even years after the initial infection.
“This is a very good vaccine for people with mild or moderate illness, but the more severe cases are not as protected, because we are seeing these symptoms again after the vaccine,” Dr David Anderson, lead author of the study and a professor of medicine at the university, told BBC News.
Clostridia difficiles are common in hospitals and other institutions across the world, and can kill people by disrupting the brain and causing inflammation.
This type of brain damage has been linked to an increase in the incidence of Alzheimer’s disease.
Dr Anderson and his team also showed that the bacteria had the ability to cause the same symptoms as the common version of the infection, but only when the immune system was compromised.
The researchers found that when the cells were damaged by the bacteria, the immune response was weakened.
“The bacteria was able to get into the brain cells, which in turn triggered the immune responses, and this resulted in the brain attacking itself,” Dr Anderson said.
“The more we study this and see the effect of the immune reactions, we think this vaccine may be able prevent these infections, and hopefully lead to new treatments for people.”
The researchers said that people should be able be vaccinated against the infection if they have symptoms such as fever, cough and fatigue, but they do not recommend this.
“It would be nice if we could see this in people, because people should get a vaccine,” said Dr Anderson.
More about brain disease,brain,brain research,brain infections,infectious,vaccine source Engidgets title Bacterial brain infections can cause severe brain damage article Researchers at the US National Institutes of Health have found that one type of bacteria in the gut of mice can cause the development of a neurological disorder known as cerebral palsy.
In a paper published in the journal Science Translator, they found that mice that were infected with this strain of Clostrina difficiliacum developed brain damage similar to that seen in people with the condition.
This strain of C. difficilia, which causes the disease known as claudication, is present in humans but is more commonly found in the animals that live in close contact with humans, which include dogs and cats.
Scientists had previously found that people with this condition also had signs of CTE, a degenerative brain disorder.
However, there was little evidence that these signs were linked to CTE in humans, so the study was the first to look at how the bacteria affected the brains of people who were infected and then later developed the disease.
Researchers found that a specific group of neurons in the brains were linked with the CTE symptoms, including a cluster of neurons linked to the areas of the brain associated with movement and balance.
They also found that these neurons were linked in a similar way to people with CTE.
“These neurons are actually very similar to those that are involved in movement and a lot of other tasks in the human brain,” said study co-author Dr Daniel R. DePinho, from the National Institute of Neurological Disorders and Stroke.
“And they’re also similar to the connections that we see in people who develop CTE.”
It is not clear whether the C.difficile infection causes CTE or if the infection itself is a precursor to CCT.
However, the study found that while C. Difficilia infections have previously been linked with CCT, it was not known how often it was linked to neurological disorders.
The study involved researchers from the NIH, the National Institutes for Health and the University at Buffalo.
Source Engadgets title Brain infections are linked to neurodegenerative diseases, study says article Researchers have found the bacteria responsible for brain infections, including those associated with Alzheimer’s, can cause neurological diseases.
Brain infections are one of the leading causes of disability in the United States.
The disease affects more than 1.3 million people in the US alone.
Brain infections have been linked in recent years to the common CTE and CTE-like symptoms, which are seen in the majority of people.
A new study from the US Centers for Disease Control and Prevention